하악골에 발생한 염증성 근섬유모세포종
Inflammatory Myofibroblastic Tumor of the Mandible
이의묵, 신동은, 안지위, 이준, 윤정훈,
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이의묵 ( Lee Eui-Mook ) - 원광대학교 치과대학 대전치과병원 구강악안면외과
신동은 ( Shin Dong-Eun ) - 원광대학교 치과대학 대전치과병원 구강병리과
안지위 ( Ahn Ji-Wee ) - 원광대학교 치과대학 대전치과병원 구강병리과
이준 ( Lee Jun ) - 원광대학교 치과대학 대전치과병원 구강악안면외과
윤정훈 ( Yoon Jung-Hoon ) - 원광대학교 치과대학 대전치과병원 구강병리과
KMID : 0829220130370020089
Abstract
Inflammatory myofibroblastic tumor (IMT) is considered as a benign tumor with local aggressive course, consisting of myofibroblastic spindle cells with an inflammatory cells infiltration. IMTs are more usually found in the lung and very rarely in the mandible. We report an IMT of the mandible in a 54-year-old man. The patient complained of pain on the right side of mandible. Radiographically, the lesion was occupied in the right mandible with bone destruction. Although the initial diagnosis was an osteomyelitis, the histopathologic examination and immunohistochemistry revealed it to be an IMT. Histologically, the lesion was composed of inflammatory cells infiltration within a variably fibroblastic or myofibroblastic spindle cell background. Immunohistochemically, spindle cells stained with smooth muscle actin (SMA) and CD68 (KP1), but uniformly negative with desmin and cytokeratin.
키워드
Inflammatory myofibroblastic tumor; Osteomyelitis; Mandible
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